ImmuPharma,
a discovery and development pharmaceutical company, said around half of the
cancer patients that have undergone treatment with its drug candidate IPP-204106
are in stable condition (their disease has stopped progressing) without any
other drug treatment. ImmuPharma's
clinical trial began last summer and up to now two lower dose levels have been
tested.
The
initial dose level of 1 mg/kg did not show any drug-related side effects. The
first patient to be treated in this study is still alive and with stable
disease 8 months after starting treatment with ImmuPharma's cancer compound. The
second dose level of 2 mg/kg also did not show any drug-related side effects.
ImmuPharma
has already begun development of the next generation of IPP-204106, the 'micro
Nucants'.
This
improved formulation comprising of small particles of the drug candidate has
shown an even more impressive efficacy in cancer models. The
clinical trial is taking place in two hospitals in Paris and one hospital in
Dijon, in France and is expected to complete in the coming months. ImmuPharma
hopes to start a Phase IIb programme later this year in patients with
glioblastoma (brain tumour), hormone-resistant prostate cancer and pancreatic
cancer. ImmuPharma CEO
Dimitri Dimitriou said the latest positive results of their cancer drug
candidate clinical trial puts the company in a good position for further major
corporate deals such as the one with their partner Cephalon on Lupuzor that is
now in a large late-stage clinical trial in the US.
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